Article
Glutamate receptor δ 1 (GRID1) genetic variation and brain structure in schizophrenia.
Journal of psychiatric research - 1 Dec 2012
Nenadic Igor, Maitra Raka, Scherpiet Sigrid, Gaser Christian, Schultz C Christoph, Schachtzabel Claudia, Smesny Stefan, Reichenbach Jürgen R, Treutlein Jens, Mühleisen Thomas W, Deufel Thomas, Cichon Sven, Rietschel Marcella, Nöthen Markus M, Sauer Heinrich, Schlösser Ralf G M
Abstract excerpt
Common genetic variation in the promoter region of the glutamate receptor delta 1 (GRID1) gene has recently been shown to confer increased risk for schizophrenia in several independent large samples. We analysed high-resolution magnetic resonance imaging (MRI) data from 62 patients with schizophrenia and 54 healthy controls using voxel-based morphometry (VBM) to assess the effect of single nucleotide polymorphism...
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