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Article

Effects of genomic copy number variants penetrant for schizophrenia on cortical thickness and surface area in healthy individuals: analysis of the UK Biobank.

The British journal of psychiatry : the journal of mental science - 1 Feb 2021

Caseras Xavier, Kirov George, Kendall Kimberley M, Rees Elliott, Legge Sophie E, Bracher-Smith Matthew, Escott-Price Valentina, Murphy Kevin

Abstract excerpt

BACKGROUND: Schizophrenia is a highly heritable disorder with undetermined neurobiological causes. Understanding the impact on brain anatomy of carrying genetic risk for the disorder will contribute to uncovering its neurobiological underpinnings. AIMS: To examine the effect of rare copy number variants (CNVs) associated with schizophrenia on brain cortical anatomy in a sample of unaffected participants from the...

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Identifiers

PMID: 32792019
DOI: 10.1192/bjp.2020.139
PMCID: PMC7844611

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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