Article
Polymorphisms of the IL-23R gene are associated with primary immune thrombocytopenia but not with the clinical outcome of pulsed high-dose dexamethasone therapy.
Annals of hematology - 1 Aug 2013
Zhan Yanxia, Hua Fanli, Ji Lili, Wang Weiguang, Zou Shanhua, Wang Xiaoyun, Li Feng, Cheng Yunfeng
Abstract excerpt
Primary immune thrombocytopenia (ITP) is an autoimmune heterogeneous disorder that is characterized by decreased platelet count. The interleukin-23 receptor (IL-23R) has been identified as a susceptibility gene for the development of multiple autoimmune diseases. To investigate the possible association of IL-23R gene single-nucleotide polymorphisms (SNPs) with ITP and the association with the clinical outcome of...
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