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Article

Influence of CYP2C9 and VKORC1 gene polymorphisms on warfarin dosage, over anticoagulation and other adverse outcomes in Indian population.

European journal of pharmacology - 15 Jun 2013

Gaikwad Tejasvita, Ghosh Kanjaksha, Kulkarni Bipin, Kulkarni Vrinda, Ross Cecil, Shetty Shrimati

Abstract excerpt

The aim of this study was to determine the frequencies of SNPs in the vitamin K epoxide reductase complex subunit 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9) genes and their effect on warfarin dose requirement, over anticoagulation and other adverse outcomes in Indian population. A total of 145 warfarin treated patients for various clinical conditions were screened for VKORC1 and CYP2C9 gene polymorphisms by...

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Source

Identifiers

PMID: 23602689
DOI: 10.1016/j.ejphar.2013.04.006

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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