Article

Genetic polymorphism of Cytochrome-P450-2C9 (CYP2C9) in Indian populations

2017-03-05

Abstract excerpt

Cytochrome-P450-2C9 ( CYP2C9 ) metabolizes wide range of drugs and highly express in human liver. Various mutations of CYP2C9 (R144C, I359L etc.), associated with drug-response, are highly diverse. We aimed to investigate the genetic diversity of CYP2C9 in Indian-subcontinent, using 1278 subjects from 36 populations. High frequency of CYP2C9*3 (0-0.179) was observed, comparative to other populations, including...

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Literature Corpus work: 68476123-8ba8-546e-89dc-0334cca33089
DOI: 10.1101/113993

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