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Article

Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing

5 Apr 2013

Abstract excerpt

BACKGROUND: Patients with prostate cancer may present with metastatic or recurrent disease despite initial curative treatment. The propensity of metastatic prostate cancer to spread to the bone has limited repeated sampling of tumor deposits. Hence, considerably less is understood about this lethal metastatic disease, as it is not commonly studied. Here we explored whole-genome sequencing of plasma DNA to scan...

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PMID: 23561577
DOI: 10.1186/gm434

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