Article
High-Resolution Genomic Profiling of Disseminated Tumor Cells in Prostate Cancer.
The Journal of molecular diagnostics : JMD - 1 Jan 2016
Wu Yu, Schoenborn Jamie R, Morrissey Colm, Xia Jing, Larson Sandy, Brown Lisha G, Qu Xiaoyu, Lange Paul H, Nelson Peter S, Vessella Robert L, Fang Min
Abstract excerpt
Circulating tumor cells and disseminated tumor cells (DTCs) are of great interest because they provide a minimally invasive window for assessing aspects of cancer biology, including tumor heterogeneity, a means to discover biomarkers of disease behavior, and a way to identify and prioritize therapeutic targets in the emerging era of precision oncology. However, the rarity of circulating tumor cells and DTCs poses...
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