Article
Molecular genetics of prostate cancer: emerging appreciation of genetic complexity.
Histopathology - 1 Jan 2012
Barbieri Christopher E, Demichelis Francesca, Rubin Mark A
Abstract excerpt
The emergence of Next Generation Sequencing is providing novel insights into cancer genomes as part of large-scale efforts by the International Cancer Genome Consortium (ICGC), as well as individual Genome Centers. Studies performing whole genome or whole exome DNA sequencing are remarkable both for the alterations discovered and equally important for the infrequent nature of recurrent mutations. Current...
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