Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring the tumor genomic landscape of aggressive prostate cancer by whole-genome sequencing of tissue or liquid biopsies.

International journal of cancer - 15 Jul 2024

Weiss Simone, Lamy Philippe, Rusan Maria, Nørgaard Maibritt, Ulhøi Benedicte Parm, Knudsen Michael, Kassentoft Christine Gaasdal, Farajzadeh Leila, Jensen Jørgen Bjerggaard, Pedersen Jakob Skou, Borre Michael, Sørensen Karina Dalsgaard

Abstract excerpt

Treatment resistance remains a major issue in aggressive prostate cancer (PC), and novel genomic biomarkers may guide better treatment selection. Circulating tumor DNA (ctDNA) can provide minimally invasive information about tumor genomes, but the genomic landscape of aggressive PC based on whole-genome sequencing (WGS) of ctDNA remains incompletely characterized. Thus, we here performed WGS of tumor tissue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Circulating Tumor DNA

Share to DNA Copy Number Variations

Share to Genomics

Share to Liquid Biopsy

Share to Prostatic Neoplasms

Share to Whole Genome Sequencing

Source

Identifiers

PMID: 38602058
DOI: 10.1002/ijc.34949

Genes

PC
PTEN
TP53
AR
BRCA1
CDK12
COL13A1
ERG
KCNH3
MYC
PTPRD
SENP3
TMPRSS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring the tumor genomic landscape of aggressive prostate cancer by whole-genome sequencing of tissue or liquid biopsies.PMID 38602058Read ↗

DNA alterations in the tumor genome and their associations with clinical outcome in prostate cancer.Semantic proximity Read ↗

Biallelic BRCA2 Mutations Shape the Somatic Mutational Landscape of Aggressive Prostate Tumors.Semantic proximity Read ↗

Integrative clinical genomics of advanced prostate cancer.Semantic proximity Read ↗

Circulating tumor DNA and tissue complementarily detect genomic alterations in metastatic hormone-sensitive prostate cancerSemantic proximity Read ↗

Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity.Semantic proximity Read ↗

Plasma genetic and genomic abnormalities predict treatment response and clinical outcome in advanced prostate cancerSemantic proximity Read ↗

Genomic analysis in active surveillance: predicting high-risk disease using tissue biomarkers.Semantic proximity Read ↗

Blood-Based Genomic Alteration Signature for Predicting Progression-Free Survival in De Novo Metastatic Hormone-Sensitive Prostate Cancer: A Real-World Study.Semantic proximity Read ↗

Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision MakingSemantic proximity Read ↗

Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer.Semantic proximity Read ↗

Integrative genomic and epigenomic profiling in plasma and urinary cell-free DNA improves early risk stratification of newly diagnosed prostate cancerSemantic proximity Read ↗

Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.