Article
The genomic and transcriptomic landscape of a HeLa cell line.
G3 (Bethesda, Md.) - 7 Aug 2013
Landry Jonathan J M, Pyl Paul Theodor, Rausch Tobias, Zichner Thomas, Tekkedil Manu M, Stütz Adrian M, Jauch Anna, Aiyar Raeka S, Pau Gregoire, Delhomme Nicolas, Gagneur Julien, Korbel Jan O, Huber Wolfgang, Steinmetz Lars M
Abstract excerpt
HeLa is the most widely used model cell line for studying human cellular and molecular biology. To date, no genomic reference for this cell line has been released, and experiments have relied on the human reference genome. Effective design and interpretation of molecular genetic studies performed using HeLa cells require accurate genomic information. Here we present a detailed genomic and transcriptomic...
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