Article
The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line.
Nature - 8 Aug 2013
Adey Andrew, Burton Joshua N, Kitzman Jacob O, Hiatt Joseph B, Lewis Alexandra P, Martin Beth K, Qiu Ruolan, Lee Choli, Shendure Jay
Abstract excerpt
The HeLa cell line was established in 1951 from cervical cancer cells taken from a patient, Henrietta Lacks. This was the first successful attempt to immortalize human-derived cells in vitro. The robust growth and unrestricted distribution of HeLa cells resulted in its broad adoption--both intent...
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