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Article

The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line.

Nature - 8 Aug 2013

Adey Andrew, Burton Joshua N, Kitzman Jacob O, Hiatt Joseph B, Lewis Alexandra P, Martin Beth K, Qiu Ruolan, Lee Choli, Shendure Jay

Abstract excerpt

The HeLa cell line was established in 1951 from cervical cancer cells taken from a patient, Henrietta Lacks. This was the first successful attempt to immortalize human-derived cells in vitro. The robust growth and unrestricted distribution of HeLa cells resulted in its broad adoption--both intentionally and through widespread cross-contamination--and for the past 60 years it has served a role analogous to that of...

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Source

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Identifiers

PMID: 23925245
DOI: 10.1038/nature12064
PMCID: PMC3740412

Genes

MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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