Article
The genomic characteristics and cellular origin of chromothripsis.
Current opinion in cell biology - 1 Jun 2016
Storchová Zuzana, Kloosterman Wigard P
Abstract excerpt
Human genomes are continuously subjected to mutations, which can drive genetic diseases and cancer. An intriguing recent finding has been the discovery of chromothripsis, a spectacular and complex form of chromosome rearrangement that can occur in the genomes of cancer cells and patients with congenital diseases. Chromothripsis has been described in a large array of human cancers and various types of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
