Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intracellular localization and association of MHC class I with porcine invariant chain.

Genetics and molecular research : GMR - 11 Mar 2013

Xu F Z, Wu S G, Yu W Y

Abstract excerpt

The objective was to investigate the intracellular localization and association of pig major histocompatibility complex (MHC) class I subunits with invariant chain (Ii). Pig MHC class I subunit cDNAs were cloned by RT-PCR and eukaryotic expression plasmids of α and β2m were constructed with fusions to red or enhanced green fluorescent protein (pDsRed2-N1-α, pEGFP-N1-α, pDsRed2-N1-β2m, and pEGFP-N1-β2m). A pig Ii...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation, B-Lymphocyte
Share to beta 2-Microglobulin
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

Share to Intracellular Space

Share to Luminescent Proteins

Share to Protein Multimerization

Share to Protein Subunits

Source

Identifiers

PMID: 23546951
DOI: 10.4238/2013.March.11.17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intracellular localization and association of MHC class I with porcine invariant chain.PMID 23546951Read ↗

[Effect of the targeted mutation of sorting motifs on the localization of porcine Ia-associated invariant chain].Semantic proximity Read ↗

Association of the Invariant Chain with Major Histocompatibility Complex Class I Molecules Directs Trafficking to Endocytic CompartmentsSemantic proximity Read ↗

Allele-dependent association of chicken MHC class I molecules with the invariant chain.Semantic proximity Read ↗

Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.Semantic proximity Read ↗

Expression of invariant chain can cause an allele-dependent increase in the surface expression of MHC class I molecules.Semantic proximity Read ↗

MHC class II-associated invariant chain contains a sorting signal for endosomal compartmentsSemantic proximity Read ↗

Identification of residues in the class II-associated Ii peptide (CLIP) region of invariant chain that affect efficiency of MHC class II-mediated antigen presentation in an allele-dependent manner.Semantic proximity Read ↗

Human-porcine MHC-I homology allows for antibody cross-reactivity.Semantic proximity Read ↗

A novel domain on HLA-DRbeta chain regulates the chaperone role of the invariant chain.Semantic proximity Read ↗

Invariant chain association with MHC class I: preference for HLA class I/beta 2-microglobulin heterodimers, specificity, and influence of the MHC peptide-binding groove.Semantic proximity Read ↗

Dynamics within tetraspanin pairs affect MHC class II expressionSemantic proximity Read ↗

Deletion of a C-terminal sequence of the class II-associated invariant chain abrogates invariant chains oligomer formation and class II antigen presentation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.