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Article

A novel domain on HLA-DRbeta chain regulates the chaperone role of the invariant chain.

Journal of cell science - 15 Oct 2006

Neumann Jürgen, Koch Norbert

Abstract excerpt

The human lymphocyte antigen (HLA) class II region encodes highly polymorphic peptide receptors, which associate in the ER to the chaperone invariant chain (Ii). Ii facilitates assembly of class II subunits to functional peptide receptors. We searched for a conserved structure on HLA-DR polypeptides that mediates contact to a previously identified proline-rich class-II-binding sequence of Ii. Major...

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Source

Identifiers

PMID: 16984974
DOI: 10.1242/jcs.03177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel domain on HLA-DRbeta chain regulates the chaperone role of the invariant chain.PMID 16984974Read ↗

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