Article
Human-porcine MHC-I homology allows for antibody cross-reactivity.
HLA - 1 Aug 2020
Forneris Nicole, Levy Heather, Burlak Christopher
Abstract excerpt
Pigs are especially useful large animal models, however, limited availability of commercially available antibodies for immunoblotting presents a significant obstacle facing preclinical xenotransplantation research. Major histocompatibility complex class I (MHC-I) molecule expression enhancement by nucleotide-binding oligomerization domain (NOD)-like receptor family with a caspase recruitment domain (CARD)...
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