Article
Allele-dependent association of chicken MHC class I molecules with the invariant chain.
Veterinary immunology and immunopathology - 15 Aug 2014
Chen Fangfang, Pan Ling, Zhang Jiegui, Zhou Xiuhong, Li Juan, Yu Weiyi
Abstract excerpt
Invariant chain (Ii) associates with MHC class I molecules in cross-presentation pathway in mouse, but the association of Ii with MHC class I molecules in chicken was not clear. In this study we selected five typical alleles from about 100 B-FA and some B-FB sequences and tested. Confocal microscopy revealed that only two alleles of α chain (CD type) rather than β chain showed incomplete co-localization with Ii...
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