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Article

Genetic analysis in young-age-of-onset Graves' disease reveals new susceptibility loci.

The Journal of clinical endocrinology and metabolism - 1 Jul 2014

Brown Rosalind S, Lombardi Angela, Hasham Alia, Greenberg David A, Gordon Joshua, Concepcion Erlinda, Hammerstad Sara S, Lotay Vaneet, Zhang Weijia, Tomer Yaron

Abstract excerpt

CONTEXT: Genetic and environmental factors play an essential role in the pathogenesis of Graves' Disease (GD). Children with GD have less exposure time to environmental factors and therefore are believed to harbor stronger genetic susceptibility than adults. OBJECTIVE: The aim of the study was to identify susceptibility loci that predispose to GD in patients with young-age-of-onset (YAO) GD. SETTING AND DESIGN:...

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Source

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Identifiers

PMID: 24684463
DOI: 10.1210/jc.2013-4358
PMCID: PMC4079314

Genes

BTNL2
CXCR4
NOTCH4
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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