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Article

Association of TNF-α promoter polymorphism and Graves' disease: an updated systematic review and meta-analysis.

Bioscience reports - 27 Apr 2018

Tu Yaqin, Fan Guorun, Zeng Tianshu, Cai Xiong, Kong Wen

Abstract excerpt

Graves' disease (GD) is a common autoimmune disorder with a genetic predisposition. Owing to the biological effect of tumor necrosis factor-α (TNF-α) on the thyroid gland and its gene location, TNF-α should be able to influence an individual's susceptibility to GD. In the present study, we conduct a meta-analysis of rs1800629 and rs361525 in TNF-α gene from all eligible case-control studies to assess the...

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PMID: 29440561
DOI: 10.1042/BSR20180143
PMCID: PMC5861325

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TNF

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