Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of HIV-1 minority variants containing the K103N drug-resistance mutation using a simple method to amplify RNA targets (SMART).

The Journal of molecular diagnostics : JMD - 1 May 2013

Morabito Kenneth, Kantor Rami, Tai Warren, Schreier Leeann, Tripathi Anubhav

Abstract excerpt

The simple method for amplifying RNA targets (SMART) was used to detect K103N, a common HIV-1 reverse transcriptase drug-resistance mutation. Novel amplifiable SMART probes served as reporter molecules for RNA sequences that are captured and separated on a microfluidic platform under zero-flow conditions. Assays were performed both off chip and in a microchip reservoir using a modified version of real-time...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance, Viral
Share to Endpoint Determination

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Reverse Transcriptase

Share to Nucleic Acid Hybridization

Share to Reproducibility of Results

Share to Sensitivity and Specificity

Share to Sequence Analysis, RNA

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 23541840
DOI: 10.1016/j.jmoldx.2013.02.005
PMCID: PMC3644729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of HIV-1 minority variants containing the K103N drug-resistance mutation using a simple method to amplify RNA targets (SMART).PMID 23541840Read ↗

Programmable fluorescent aptamer-based RNA switches for rapid identification of point mutations.Semantic proximity Read ↗

OLA-Simple: A software-guided HIV-1 drug resistance test for low-resource laboratories.Semantic proximity Read ↗

Population-based nanopore sequencing of the HIV-1 pangenome to identify drug resistance mutations.Semantic proximity Read ↗

Near-point-of-care assay with a visual readout for detection of HIV-1 drug resistance mutations: A proof-of-concept study.Semantic proximity Read ↗

Multiplex Solid-Phase Melt Curve Analysis for the Point-of-Care Detection of HIV-1 Drug Resistance.Semantic proximity Read ↗

Simultaneous Detection of Major Drug Resistance Mutations in the Protease and Reverse Transcriptase Genes for HIV-1 Subtype C by Use of a Multiplex Allele-Specific AssaySemantic proximity Read ↗

PANDAA intentionally violates conventional qPCR design to enable durable, mismatch-agnostic detection of highly polymorphic pathogens.Semantic proximity Read ↗

PANDAA-monium: Intentional violations of conventional qPCR design enables rapid, HIV-1 subtype-independent drug resistance SNP detectionSemantic proximity Read ↗

Multiplex qPCR Assay for HIV-1 Proviral DNA Detection and Subtype Characterization: Exploiting Quenching of Multiple Fluorophores with a Single Quencher Operating in<i>Trans</i>Semantic proximity Read ↗

Analytical Sensitivity of the SalivaDirect™ Assay on the Liberty16 for detecting SARS-CoV-2 B.1.1.529 (“Omicron”)Semantic proximity Read ↗

A single variant sequencing method for sensitive and quantitative detection of HIV-1 minority variants.Semantic proximity Read ↗

MultiCode-RTx real-time PCR system for detection of subpopulations of K65R human immunodeficiency virus type 1 reverse transcriptase mutant viruses in clinical samples.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.