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Article

Rapid, low-cost, and portable molecular detection of HIV-1 subtype B and HCV 1a directly from blood.

Microbiology spectrum - 1 Sept 2026

Tang David M, Michalak Karen, Nguyen Kelvin, Lacap Philip, Kim John, McLaren Paul J

Abstract excerpt

Accessible molecular diagnostics for human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV) remain constrained by the cost and infrastructure requirements of existing molecular point-of-care platforms. In this study, we describe a portable, proof-of-concept molecular workflow with a total runtime of 32 min for the simultaneous qualitative detection of HIV-1 subtype B and HCV genotype 1a directly from...

Read the complete abstract on PubMed

Topics

HIV-1
Humans
Hepacivirus
Hepatitis C
Nucleic Acid Amplification Techniques
HIV Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Molecular Diagnostic Techniques

Rapid Diagnostic Tests

RNA, Viral

Sensitivity and Specificity

Genotype

Point-of-Care Systems

Source

Open in PubMed Open full text

Identifiers

PMID: 42554489
DOI: 10.1128/spectrum.00416-26
PMCID: PMC13532246

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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