Article
Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer.
Cancer epidemiology - 1 Aug 2013
Akbari Mohammad R, Anderson Laura N, Buchanan Daniel D, Clendenning Mark, Jenkins Mark A, Win Aung Ko, Hopper John L, Giles Graham G, Nam Robert, Narod Steven, Gallinger Steven, Cleary Sean P
Abstract excerpt
INTRODUCTION: The HOXB13 pGly84Glu mutation has recently been associated with an increased risk of prostate cancer but the association of other cancer sites with this allele has not been assessed. Data has suggested that HOXB13 expression levels are decreased in colorectal cancer (CRC) cell lines indicating this gene may be involved in colorectal tumourigenesis. METHODS: To evaluate a potential association of...
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