Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The HOXB13 G84E Mutation Is Associated with an Increased Risk for Prostate Cancer and Other Malignancies.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2015

Beebe-Dimmer Jennifer L, Hathcock Matthew, Yee Cecilia, Okoth Linda A, Ewing Charles M, Isaacs William B, Cooney Kathleen A, Thibodeau Stephen N

Abstract excerpt

BACKGROUND: A rare nonconservative substitution (G84E) in the HOXB13 gene has been shown to be associated with risk of prostate cancer. DNA samples from male patients included in the Mayo Clinic Biobank (MCB) were genotyped to determine the frequency of the G84E mutation and its association with various cancers. METHODS: Subjects were genotyped using a custom TaqMan (Applied Biosystems) assay for G84E...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Heterozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeodomain Proteins

Share to Leukemia

Share to Mutation Rate

Share to Pedigree

Share to Prostatic Neoplasms

Share to Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 26108461
DOI: 10.1158/1055-9965.EPI-15-0247
PMCID: PMC4560608

Genes

HOXB13
IMPACT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The HOXB13 G84E Mutation Is Associated with an Increased Risk for Prostate Cancer and Other Malignancies.PMID 26108461Read ↗

Association between germline HOXB13 G84E mutation and risk of prostate cancer.Semantic proximity Read ↗

Association of HOXB13 G84E with prostate cancer among 592,158 menSemantic proximity Read ↗

Association of HOXB13 G84E With Prostate Cancer Among 592,158 Men.Semantic proximity Read ↗

The G84E mutation in the HOXB13 gene is associated with an increased risk of prostate cancer in Poland.Semantic proximity Read ↗

Prevalence of the HOXB13 G84E mutation in Danish men undergoing radical prostatectomy and its correlations with prostate cancer risk and aggressiveness.Semantic proximity Read ↗

HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).Semantic proximity Read ↗

Prevalence of the HOXB13 G84E prostate cancer risk allele in men treated with radical prostatectomy.Semantic proximity Read ↗

HOXB13 G84E mutation in Finland: population-based analysis of prostate, breast, and colorectal cancer risk.Semantic proximity Read ↗

G84E mutation in HOXB13 is firmly associated with prostate cancer risk: a meta-analysis.Semantic proximity Read ↗

Testing for the recurrent HOXB13 G84E germline mutation in men with clinical indications for prostate biopsy.Semantic proximity Read ↗

Prevalence of the HOXB13 G84E mutation among unaffected men with a family history of prostate cancer.Semantic proximity Read ↗

The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trial.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.