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Article

Association between germline HOXB13 G84E mutation and risk of prostate cancer.

Journal of the National Cancer Institute - 22 Aug 2012

Akbari Mohammad R, Trachtenberg John, Lee Justin, Tam Stephanie, Bristow Robert, Loblaw Andrew, Narod Steven A, Nam Robert K

Abstract excerpt

Recently, a G84E mutation in HOXB13, a gene involved in prostate development, was shown to be strongly associated with an increased risk of prostate cancer. To confirm this association in a screening setting, we conducted a case-control study and sequenced germline DNA from peripheral leukocytes of 1843 men diagnosed with prostate cancer (case subjects) and 2225 men without prostate cancer (control subjects) for...

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PMID: 22781434
DOI: 10.1093/jnci/djs288

Genes

HOXB13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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