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Article

The HOXB13 p.Gly84Glu mutation is not associated with the risk of breast cancer.

Breast cancer research and treatment - 1 Dec 2012

Akbari Mohammad R, Kluźniak Wojciech, Rodin Rachelle, Li Song, Wokołorczyk Dominika, Royer Robert, Kashyap Aniruddh, Menkiszak Janusz, Lubinski Jan, Narod Steven A, Cybulski Cezary

Abstract excerpt

Recently, the HOXB13 gene has been shown to be a susceptibility gene for prostate cancer. HOXB13 is overexpressed in breast cancer tissues and HOXB13 expression in combination with low expression of IL17BR is predictive for a tamoxifen response in ER-positive breast cancers. Based on observations, we hypothesized that the HOXB13 p.Gly84Glu mutation might be associated with breast cancer risk. We genotyped this...

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Identifiers

PMID: 23099437
DOI: 10.1007/s10549-012-2295-y
PMCID: PMC3511696

Genes

HOXB13

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The HOXB13 p.Gly84Glu mutation is not associated with the risk of breast cancer.PMID 23099437Read ↗

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.Semantic proximity Read ↗

Recurrent HOXB13 mutations in the Dutch population do not associate with increased breast cancer risk.Semantic proximity Read ↗

Germline HOXB13 p.Gly84Glu mutation and cancer susceptibility: a pooled analysis of 25 epidemiological studies with 145,257 participates.Semantic proximity Read ↗

Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer.Semantic proximity Read ↗

Germline HOXB13 G84E mutation carriers and risk to twenty common types of cancer: results from the UK Biobank.Semantic proximity Read ↗

Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients.Semantic proximity Read ↗

HOXB13, a high-risk prostate cancer gene, also confers risk for breast cancer: novel variants of clinical significance, especially in hormone-positive patients.Semantic proximity Read ↗

Prevalence of the HOXB13 G84E mutation in Danish men undergoing radical prostatectomy and its correlations with prostate cancer risk and aggressiveness.Semantic proximity Read ↗

G84E mutation in HOXB13 is firmly associated with prostate cancer risk: a meta-analysis.Semantic proximity Read ↗

Germline homeobox B13 (HOXB13) G84E mutation and prostate cancer risk in European descendants: a meta-analysis of 24,213 cases and 73, 631 controls.Semantic proximity Read ↗

The G84E mutation in the HOXB13 gene is associated with an increased risk of prostate cancer in Poland.Semantic proximity Read ↗

Evaluation of homeobox protein B13 (HOXB13) gene G84E mutation in patients with prostate cancer.Semantic proximity Read ↗

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