Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients.

doi:10.1371/journal.pone.0132728

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Article

Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients.

PloS one - 1 Jan 2015

Maia Sofia, Cardoso Marta, Pinto Pedro, Pinheiro Manuela, Santos Catarina, Peixoto Ana, Bento Maria José, Oliveira Jorge, Henrique Rui, Jerónimo Carmen, Teixeira Manuel R

Abstract excerpt

The HOXB13 germline variant G84E (rs138213197) was recently described in men of European descent, with the highest prevalence in Northern Europe. The G84E mutation has not been found in patients of African or Asian ancestry, which may carry other HOXB13 variants, indicating allelic heterogeneity depending on the population. In order to gain insight into the full scope of coding HOXB13 mutations in Portuguese...

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Identifiers

PMID: 26176944
DOI: 10.1371/journal.pone.0132728
PMCID: PMC4503425

Genes

HOXB13

Variants

rs138213197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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