Article
Association of paraoxonase 1 L55M and Q192R single-nucleotide polymorphisms with age-related macular degeneration.
Retina (Philadelphia, Pa.) - 1 Oct 2013
Söğüt Erkan, Ortak Hüseyin, Aydoğan Leyla, Benlı Ismaıl
Abstract excerpt
PURPOSE: To determine if paraoxonase 1 (PON1) gene polymorphisms have an effect on the risk of having age-related macular degeneration (AMD). METHODS: The study population consisted of 142 patients who were diagnosed with either exudative or atrophic AMD and 138 sex- and age-matched controls without AMD. Genotyping of the PON1 L55M and Q192R single-nucleotide polymorphisms was performed using real-time polymerase...
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