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Article

Protective effect of paraoxonase 1 gene variant Gln192Arg in age-related macular degeneration.

American journal of ophthalmology - 1 Mar 2010

Pauer Gayle J T, Sturgill Gwen M, Peachey Neal S, Hagstrom Stephanie A

Abstract excerpt

PURPOSE: Age-related macular degeneration (AMD) is the leading cause of blindness among older adults, in which oxidative damage may play a pivotal role. Paraoxonase 1 (PON1) protects against oxidative damage and has been evaluated for its involvement in aging diseases including AMD. This study investigated whether PON1 gene polymorphisms associate with AMD. DESIGN: Case-control association study. METHODS: We...

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Source

Open in PubMed Open full text

Identifiers

PMID: 20042177
DOI: 10.1016/j.ajo.2009.09.024
PMCID: PMC3026437

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Protective effect of paraoxonase 1 gene variant Gln192Arg in age-related macular degeneration.PMID 20042177Read ↗

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