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Article

Paraoxonase 1 (PON1)-L55M among common variants in the coding region of the paraoxonase gene family may contribute to the glycemic control in type 2 diabetes.

Clinica chimica acta; international journal of clinical chemistry - 1 Sept 2018

Mahrooz Abdolkarim, Hashemi-Soteh Mohammad Bagher, Heydari Masoud, Boorank Ruzbeh, Ramazani Fatemeh, Mahmoudi Ali, Kianmehr Anvarsadat, Alizadeh Ahad

Abstract excerpt

OBJECTIVE: Genome studies have shown that the genes encoding paraoxonase 1 (PON1) and PON2 are associated with glucose metabolism. The goal of this study was to simultaneously evaluate the association between functional variants in PON1 and PON2 genes and susceptibility for type 2 diabetes (T2D) and determine whether they can affect glycemic control. METHODS: We performed a case-control study with 145 newly...

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Aryldialkylphosphatase
Blood Glucose
Diabetes Mellitus, Type 2
Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Genetic Variation

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PMID: 29782842
DOI: 10.1016/j.cca.2018.05.037

Genes

PON1
PON2

Variants

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