Article
Association of genetic variants at CETP, AGER, and CYP4F2 locus with the risk of atrophic age-related macular degeneration.
Molecular genetics & genomic medicine - 1 Sept 2020
Liutkeviciene Rasa, Vilkeviciute Alvita, Kriauciuniene Loresa, Banevicius Mantas, Budiene Brigita, Stanislovaitiene Daiva, Zemaitiene Reda, Deltuva Vytenis P
Abstract excerpt
BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly individuals. The etiology of AMD includes environmental and genetic factors. METHODS: We aimed to determine the association between CETP (rs5882; rs708272; rs3764261; rs1800775; rs2303790), AGER (; ), and CYP4F2 () gene polymorphisms and development of atrophic AMD. About 52 patients with...