Article
The Role of SNPs in IL1RL1 and IL1RAP Genes in Age-related Macular Degeneration Development and Treatment Efficacy.
In vivo (Athens, Greece) - 1 Jan 2000
Vilkeviciute Alvita, Bastikaityte Neringa, Mockute Ruta, Cebatoriene Dzastina, Kriauciuniene Loresa, Balciuniene Jurate, Zemaitiene Reda, Liutkeviciene Rasa
Abstract excerpt
BACKGROUND: Age-related macular degeneration (AMD) affects the central part of the retina and causes blindness. In developed countries, AMD occurs in people over 50 years old. Important factors for AMD pathogenesis are an immune response, inflammation, and genetic factors. This study aimed to determine the impact of IL1RL1 rs1041973 and IL1RAP rs4624606 single nucleotide polymorphisms (SNPs) on the occurrence of...
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