Article
Association of the M55L and Q192R paraoxonase gene polymorphisms with age-related macular degeneration.
American journal of ophthalmology - 1 Oct 2004
Baird Paul N, Chu Diep, Guida Elizabeth, Vu Hien T V, Guymer Robyn
Abstract excerpt
PURPOSE: To investigate the reported association of the two single-nucleotide polymorphisms (SNPs) of the paraoxonase gene (PON1), Met-Leu 55 (M55L) and Gln-Arg 192 (Q192R), in individuals of Anglo-Celtic descent who have age-related macular degeneration (AMD). DESIGN: Case-control association study. METHODS: Sixty-two individuals with late (end-stage) AMD and 115 control subjects (without AMD) were included in...
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