Article
Association and cumulative effects of GWAS-identified genetic variants for nonsyndromic orofacial clefts in a Chinese population.
Environmental and molecular mutagenesis - 1 May 2013
Pan Yongchu, Han Yue, Zhang Hongchuang, Zhou Lian, Li Dandan, Cai Qi, Ma Junqing, Zhang Weibing, Wang Lin
Abstract excerpt
A recent genome-wide meta-analysis identified six new susceptible genetic variants for nonsyndromic orofacial clefts (NSOC), but it was still unknown whether these newly identified variants were associated with NSOC susceptibility in Chinese populations. In this study, we genotyped these variants in a case-control study of 602 NSOC cases and 605 controls and found that four of these variants (rs7590268,...
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