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Article

Investigating SPRY2 Single-Nucleotide Polymorphisms in the Etiology of Nonsyndromic Orofacial Cleft in the Chinese Han Population.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Sept 2026

Yang Meng Xi, Duan Shi Jun, Jia Sixuan, Shi Bing, Jia Zhong Lin

Abstract excerpt

ObjectiveThis study aimed to explore the relationship between the SPRY2 gene and nonsyndromic orofacial cleft (NSOC) in the Chinese Han population.DesignA case-control study was conducted with a large cohort to analyze genetic associations.SettingThe study was conducted in China, focusing on the Chinese Han ethnic group.Patients, ParticipantsThe study included 2494 Chinese Han patients with NSOC and 2255 healthy...

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Identifiers

PMID: 41212736
DOI: 10.1177/10556656251393169

Genes

SPRY2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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