Article
Genetics of nonsyndromic orofacial clefts.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jan 2012
Rahimov Fedik, Jugessur Astanand, Murray Jeffrey C
Abstract excerpt
With an average worldwide prevalence of approximately 1.2/1000 live births, orofacial clefts are the most common craniofacial birth defects in humans. Like other complex disorders, these birth defects are thought to result from the complex interplay of multiple genes and environmental factors. Significant progress in the identification of underlying genes and pathways has benefited from large populations...
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