Article
[Progress in next-generation sequencing research of non-syndromic oral clefts].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 10 Mar 2018
Wang M Y, Liu D J, Huang H, Li W Y, Zhou R, Zhu H P, Zhou Z B, Wu T
Abstract excerpt
Non-syndromic oral clefts (NSOC) are among the most common birth defects. The prevalence of NSOC is 1.13-1.30 per 1 000 live births in China, which is higher than those in other major ethnic groups. The etiology of NSOC is complex and heterogeneous, which involves both genetic and environmental risk factors. Although genome-wide association studies have identified a number of risk loci, these loci can only...
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