Article
Replication of two novel susceptibility loci for non-syndromic orofacial clefts in a Chinese population.
Oral diseases - 1 Apr 2011
Pan Y, Ma J, Zhang W, Wang Y, Wang Y, Zhang H, Wang M, Zhang Z, Wang L
Abstract excerpt
OBJECTIVES: Non-syndromic orofacial clefts (NSOC) are the most common developmental disorders in human beings. Recently, two genome-wide association studies in European Caucasians identified three novel NSOC susceptibility loci: rs987525 on 8q24, rs7078160 on 10q25.3, and rs223371 on 17q22. The aim of this study was to determine the association of these polymorphisms with NSOC susceptibility and its subgroups in...
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