Article
The Evolution of Gene Sequencing Technologies: Unveiling Genetic Architecture of Nonsyndromic Orofacial Clefts.
Genetics research - 1 Jan 2026
Zhao Haolang, Zhang Sidi, Zhu Haoyun, Jia Zhonglin
Abstract excerpt
Nonsyndromic orofacial clefts (NSOC) are common congenital craniofacial developmental defects. Current evidence suggests that genetic factors, environmental exposures, and their interactions jointly contribute to the development of the disease. Owing to the high heritability of NSOC, identifying susceptibility genes and loci is a central focus of etiological research. This review summarizes key findings in the...
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