Article
Polymorphisms in toll-like receptors 2, 4 and 5 are associated with Legionella pneumophila infection.
Infection - 1 Oct 2013
Zhang F, Gao X-D, Wu W-W, Gao Y, Zhang Y-W, Wang S-P
Abstract excerpt
PURPOSE: To investigate whether single-nucleotide polymorphisms (SNPs) in toll-like receptors (TLR) 2, 4 and 5 affect the susceptibility of Legionella pneumophila infection in a Han Chinese population by in vitro assay. METHODS: Fifty-four (n = 54) healthy subjects were genotyped for SNPs (TLR2 (C597T) [rs3804099], TLR4 (G2244A), TLR4 (A2299G) [AF177765] and TLR5 (C1174T) [rs5744168]). Peripheral blood...
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