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Article

Screening toll-like receptor markers to predict latent tuberculosis infection and subsequent tuberculosis disease in a Chinese population.

BMC medical genetics - 1 Apr 2015

Wu Linlin, Hu Yi, Li Dange, Jiang Weili, Xu Biao

Abstract excerpt

BACKGROUND: We investigated whether polymorphisms in the toll-like receptor genes or gene-gene interactions are associated with susceptibility to latent tuberculosis infection (LTBI) or subsequent pulmonary tuberculosis (PTB) in a Chinese population. METHODS: Two matched case-control studies were undertaken. Previously reported polymorphisms in the toll-like receptors (TLRs) were compared between 422 healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25928077
DOI: 10.1186/s12881-015-0166-1
PMCID: PMC4421918

Genes

TLR2
TLR4
TLR8
TLR9
TIRAP
TLR1
TLR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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