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Article

Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion.

Nucleic acids research - 1 May 2013

Liu Yuying, Conaway LaShardai, Rutherford Bethard Jennifer, Al-Ayoubi Adnan M, Thompson Bradley Amber, Zheng Hui, Weed Scott A, Eblen Scott T

Abstract excerpt

Alternative mRNA splicing is a mechanism to regulate protein isoform expression and is regulated by alternative splicing factors. The alternative splicing factor 45 (SPF45) is overexpressed in cancer, although few biological effects of SPF45 are known, and few splicing targets have been identifie...

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Identifiers

PMID: 23519612
DOI: 10.1093/nar/gkt170
PMCID: PMC3643583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23519612-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion.PMID 23519612Read ↗

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