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Article

CD151 promotes cancer cell metastasis via integrins α3β1 and α6β1 in vitro.

Molecular medicine reports - 1 Dec 2012

Fei Yujie, Wang Ji, Liu Weifeng, Zuo Houjuan, Qin Jin, Wang Daowen, Zeng Hesong, Liu Zhengxiang

Abstract excerpt

CD151 is a member of the tetraspanin family that is implicated as a promoter of the tumor metastasis of malignant cells. Tetraspanins form membrane complexes with integrins. In the present study, we constructed a CD151-AAA mutant to assess the roles of Rac, cdc42 and phospho-Rac/cdc42 (P-Rac/cdc42) and the effects of CD151‑integrin complexes on the proliferation,...

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Identifiers

PMID: 23007325
DOI: 10.3892/mmr.2012.1095

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CCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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