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Mechanism and function of CEACAM1 splice isoforms

1 Dec 2024

Abstract excerpt

BACKGROUND: Alternative splicing is a fundamental mechanism in the post-transcriptional regulation of genes. The multifunctional transmembrane glycoprotein receptor carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) undergoes extensive alternative splicing to allow for tunable functions in cell signalling, adhesion and modulation of immune and metabolic responses. Splice isoforms that differ in...

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PMID: 39674874
DOI: 10.1111/eci.14350

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