Article
A polymorphic microsatellite in the tumor necrosis factor alpha promoter identifies an allele unique to the NZW mouse strain.
The Journal of experimental medicine - 1 Jun 1990
Jongeneel C V, Acha-Orbea H, Blankenstein T
Abstract excerpt
We have amplified a (CA)n:(GT)n microsatellite from the TNF promoters of a panel of mouse strains using the polymerase chain reaction. The length of the microsatellites was polymorphic, with eight alleles observed among 15 inbred strains bearing seven distinct H-2 haplotypes, and four outbred str...
Topics
- Alleles
- Animals
- Base Sequence
- DNA
- DNA, Satellite
- Genetic Markers
- Haplotypes
- Liver
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Species Specificity
- Tumor Necrosis Factor-alpha
