Comparative expression of TNF-alpha alleles from normal and autoimmune-prone MHC haplotypes.

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Article

Comparative expression of TNF-alpha alleles from normal and autoimmune-prone MHC haplotypes.

Journal of inflammation - 1 Jan 1995

Bazzoni F, Beutler B

Abstract excerpt

The tumor necrosis factor-alpha (TNF-alpha, or TNF) genes of NOD mice and NZW mice are reportedly underexpressed relative to the TNF genes of control mice in lipopolysaccharide (LPS)-induced peritoneal macrophages. These findings, as well as the well-known major histocompatibility complex (MHC) l...

Topics

Alleles
Animals
Autoimmune Diseases
Base Sequence
Cells, Cultured
Crosses, Genetic
Haplotypes
Lipopolysaccharides
Macrophages, Peritoneal
Major Histocompatibility Complex
Mice
Mice, Inbred BALB C
Mice, Inbred NOD
Mice, Inbred NZB
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 7583356

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7583356-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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