Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism of the mouse TNF-alpha locus: sequence studies of the 3'-untranslated region and first intron.

Gene - 30 Jul 1993

Beutler B, Brown T

Abstract excerpt

We have sequenced the 3'-untranslated region (3'-UTR) and first intron of six strains of Mus musculus, as well as M. spretus, M. castaneus, and M. shanghai. A marked degree of polymorphism was evident in the sequences, and among all of the strains, no two haplotypes were identical. Of particular note, insertional mutations modifying the 5'-TTATTTAT sequence in the 3'-UTR, which in its RNA form acts as a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Mutational Analysis
Share to Haplotypes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Polymorphism, Restriction Fragment Length

Share to Restriction Mapping

Source

Identifiers

PMID: 8100792
DOI: 10.1016/0378-1119(93)90280-g

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism of the mouse TNF-alpha locus: sequence studies of the 3'-untranslated region and first intron.PMID 8100792Read ↗

A Similar Mutation in the AAUU-Rich Elements of the Mouse TNF Gene Results in a Distinct Ileocolitic Phenotype: A New Strain of TNF-Overexpressing Mice.Semantic proximity Read ↗

Polymorphisms in the Tnfa gene of different inbred mouse strains.Semantic proximity Read ↗

A polymorphic microsatellite in the tumor necrosis factor alpha promoter identifies an allele unique to the NZW mouse strain.Semantic proximity Read ↗

Polymorphisms of the tumor necrosis factor alpha locus among autoimmune disease susceptible and resistant inbred rat strains.Semantic proximity Read ↗

Genetic variation in mouse apolipoprotein A-IV due to insertion and deletion in a region of tandem repeats.Semantic proximity Read ↗

Comparative analyses of single-nucleotide polymorphisms in the TNF promoter region provide further validation for the vervet monkey model of obesity.Semantic proximity Read ↗

Sequence divergence of Mus spretus and Mus musculus across a skin cancer susceptibility locus.Semantic proximity Read ↗

Genetic engineering in the mouse: tuning TNF/TNFR expression.Semantic proximity Read ↗

Spontaneous retrotransposon insertion into TNF 3'UTR causes heart valve disease and chronic polyarthritis.Semantic proximity Read ↗

Sequence analysis of the regulatory region of the TNF-RII gene in Polish Holstein-Friesian cows.Semantic proximity Read ↗

Mitochondrial DNA sequence variation in the eastern house mouse, Mus musculus: comparison with other house mice and report of a 75-bp tandem repeat.Semantic proximity Read ↗

Nucleotide sequence of the tumor necrosis factor: a gene in seven different inbred mouse strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.