Article
Polymorphism of the mouse TNF-alpha locus: sequence studies of the 3'-untranslated region and first intron.
Gene - 30 Jul 1993
Beutler B, Brown T
Abstract excerpt
We have sequenced the 3'-untranslated region (3'-UTR) and first intron of six strains of Mus musculus, as well as M. spretus, M. castaneus, and M. shanghai. A marked degree of polymorphism was evident in the sequences, and among all of the strains, no two haplotypes were identical. Of particular...
Topics
- Animals
- Base Sequence
- DNA Mutational Analysis
- DNA Transposable Elements
- Haplotypes
- Introns
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Mutation
- Poly A
- Polymorphism, Restriction Fragment Length
- Protein Biosynthesis
- Repressor Proteins
- Restriction Mapping
- Species Specificity
- Tumor Necrosis Factor-alpha