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Article

The -144C/A polymorphism in the promoter of HSP90beta is associated with multiple organ dysfunction scores.

PloS one - 1 Jan 2013

Zhao Yan, Tao Liju, Jiang Dongpo, Chen Xingyun, Li Ping, Ning Yalei, Xiong Renping, Liu Ping, Peng Yizhi, Zhou Yuan-Guo

Abstract excerpt

INTRODUCTION: Variations in genetic background are the leading cause of differential susceptibility to traumatic infection. Heat shock protein 90 (HSP90), a broadly distributed and conserved molecule, regulates inflammation under stressful and traumatic conditions. However, the relationships between HSP90 genetic polymorphisms, post-traumatic inflammatory responses and organ function remain unknown. METHODS: A...

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Identifiers

PMID: 23516526
DOI: 10.1371/journal.pone.0058646
PMCID: PMC3596273

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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