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Article

Clinical relevance of 13 cytokine gene polymorphisms in Chinese major trauma patients.

Intensive care medicine - 1 Jul 2010

Gu Wei, Zeng Ling, Zhou Jian, Jiang Dong-po, Zhang Lianyang, Du Ding-yuan, Hu Ping, Chen Kehong, Liu Qin, Wang Zheng-guo, Jiang Jian-xin

Abstract excerpt

PURPOSE: To determine the clinical relevance of 13 reported common single-nucleotide polymorphisms (SNPs) of cytokine genes in patients with major trauma. METHODS: Thirteen SNPs in nine key cytokine genes were selected for association study in 308 patients with major trauma on the basis of previous functional or association data. An allele-specific oligonucleotide array was developed and used to genotype 308...

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PMID: 20217044
DOI: 10.1007/s00134-010-1797-5

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