Article
KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers.
British journal of cancer - 30 Apr 2013
Phipps A I, Buchanan D D, Makar K W, Win A K, Baron J A, Lindor N M, Potter J D, Newcomb P A
Abstract excerpt
BACKGROUND: Mutations in the Kirsten Ras (KRAS) oncogene are common in colorectal cancer (CRC). The role of KRAS-mutation status as a prognostic factor, however, is unclear. We evaluated the relationship between KRAS-mutation status and CRC survival, considering heterogeneity in this association by tumour and patient characteristics. METHODS: The population-based study included individuals diagnosed with CRC...
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