Article
KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers.
British journal of cancer - 30 Apr 2013
Phipps A I, Buchanan D D, Makar K W, Win A K, Baron J A, Lindor N M, Potter J D, Newcomb P A
Abstract excerpt
BACKGROUND: Mutations in the Kirsten Ras (KRAS) oncogene are common in colorectal cancer (CRC). The role of KRAS-mutation status as a prognostic factor, however, is unclear. We evaluated the relationship between KRAS-mutation status and CRC survival, considering heterogeneity in this association...
Topics
- Adult
- Aged
- Colorectal Neoplasms
- Female
- Genes, ras
- Humans
- Male
- Middle Aged
- Mutation
- SEER Program
- Survival Rate
- Washington
- Young Adult
