Article
The Association Between Mutations in BRAF and Colorectal Cancer-Specific Survival Depends on Microsatellite Status and Tumor Stage.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Feb 2019
Bläker Hendrik, Alwers Elizabeth, Arnold Alexander, Herpel Esther, Tagscherer Katrin E, Roth Wilfried, Jansen Lina, Walter Viola, Kloor Matthias, Chang-Claude Jenny, Brenner Hermann, Hoffmeister Michael
Abstract excerpt
BACKGROUND & AIMS: Colorectal tumors with mutations in BRAF and microsatellite stability (MSS) have been associated with adverse outcomes of patients. Combined tests for microsatellite instability-high (MSI-H) and BRAF mutations might therefore be used in risk assessment, particularly for patients with stage II tumors. We investigate the stage-specific prognostic value of combined testing for MSI-H and BRAF for...
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