The Association Between Mutations in BRAF and Colorectal Cancer-Specific Survival Depends on Microsatellite Status and Tumor Stage.

doi:10.1016/j.cgh.2018.04.015

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Article

The Association Between Mutations in BRAF and Colorectal Cancer-Specific Survival Depends on Microsatellite Status and Tumor Stage.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Feb 2019

Bläker Hendrik, Alwers Elizabeth, Arnold Alexander, Herpel Esther, Tagscherer Katrin E, Roth Wilfried, Jansen Lina, Walter Viola, Kloor Matthias, Chang-Claude Jenny, Brenner Hermann, Hoffmeister Michael

Abstract excerpt

BACKGROUND & AIMS: Colorectal tumors with mutations in BRAF and microsatellite stability (MSS) have been associated with adverse outcomes of patients. Combined tests for microsatellite instability-high (MSI-H) and BRAF mutations might therefore be used in risk assessment, particularly for patient...

Topics

Adult
Aged
Aged, 80 and over
Colorectal Neoplasms
Female
Genetic Predisposition to Disease
Germany
Humans
Male
Microsatellite Repeats
Middle Aged
Mutation
Neoplasm Staging

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prognosis

Proto-Oncogene Proteins B-raf

Retrospective Studies

Risk Assessment

Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 29660527
DOI: 10.1016/j.cgh.2018.04.015

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-29660527-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.