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Article

Activating KRAS mutation is prognostic only among patients who receive preoperative chemotherapy before resection of colorectal liver metastases.

Journal of surgical oncology - 1 Sept 2016

Margonis Georgios Antonios, Kim Yuhree, Sasaki Kazunari, Samaha Mario, Buettner Stefan, Amini Neda, Pawlik Timothy M

Abstract excerpt

BACKGROUND AND OBJECTIVES: While the prognostic role of KRAS status after resection of CRLM has been previously explored, the importance of KRAS status relative to the receipt of preoperative chemotherapy remains largely unknown. METHODS: A total of 430 patients who underwent curative-intent surgery for CRLM between 2000 and 2015 and who had available KRAS genotype data were identified. Data regarding KRAS...

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Share to Antineoplastic Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins p21(ras)

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Source

Identifiers

PMID: 27264476
DOI: 10.1002/jso.24319

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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